Embryology in the Quran: Difference between revisions

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(→‎The Timing of These Processes: archived Galjaard paper and added google books preview links for main other sources)
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A very detailed account of musculo-skeletal development in the human limb by clinical-geneticist Robert Jan Galjaard can be read online.<ref>Galjaard, R.J.H. [http://repub.eur.nl/res/pub/10474/030924_Galjaard,%20Robert-Jan%20Harmen.pdf Mapping Studies of Congenital Limb Anomalies]. Ablasserdam: Haveka, B.V., 2003, page 16 [http://www.webcitation.org/6lFwBQq9z webcitation archive link]</ref> It details that muscle precursor cells migrate from the somites into the limb buds (ca. day 26), well before the condensing core of mesenchyme has started to chondrify into cartilage bone models in the upper part of the upper limb (ca. day 37), followed by the lower part (ca. day 41). The myoblasts have grouped into distinct masses by this stage and are differentiating into muscle fibres. The upper limbs later start to ossify (ca. day 54).
A very detailed account of musculo-skeletal development in the human limb by clinical-geneticist Robert Jan Galjaard can be read online.<ref>Galjaard, R.J.H. [http://repub.eur.nl/res/pub/10474/030924_Galjaard,%20Robert-Jan%20Harmen.pdf Mapping Studies of Congenital Limb Anomalies]. Ablasserdam: Haveka, B.V., 2003, page 16 [http://www.webcitation.org/6lFwBQq9z webcitation archive link]</ref> It details that muscle precursor cells migrate from the somites into the limb buds (ca. day 26), well before the condensing core of mesenchyme has started to chondrify into cartilage bone models in the upper part of the upper limb (ca. day 37), followed by the lower part (ca. day 41). The myoblasts have grouped into distinct masses by this stage and are differentiating into muscle fibres. The upper limbs later start to ossify (ca. day 54).


Professor Peter Law confirms that myoblasts are found in the limb buds day 26.<ref>Law, Peter et al., '''Pioneering Human Myoblast Genome Therapy as a Platform Technology of Regenerative Medicine.''' In: Stem Cell Therapy. Erik Greer (Editor). Nova Science Publishers, Inc. 2006. Page 3.</ref>
Professor Peter Law confirms that myoblasts are found in the limb buds day 26.<ref>Law, Peter et al., ''Pioneering Human Myoblast Genome Therapy as a Platform Technology of Regenerative Medicine.'' In: Stem Cell Therapy. Erik Greer (Editor). Nova Science Publishers, Inc. 2006. Page 3.</ref>


Myoblasts have aggregated into ventral and dorsal masses in the upper limb by day 36 and the start of chondrification.<ref>Sivakumar, B. et. al. ''Congenital Hand Differences'' in Farhadieh, R. et. al. (ed.) Plastic and Reconstructive Surgery: Approaches and Techniques, Chichester: Wiley, 2015, p.660 [https://books.google.co.uk/books?id=tCq9BgAAQBAJ&pg=PA660#v=onepage&q&f=false Google books preview]</ref>
Myoblasts have aggregated into ventral and dorsal masses in the upper limb by day 36 and the start of chondrification.<ref>Sivakumar, B. et. al. ''Congenital Hand Differences'' in Farhadieh, R. et. al. (ed.) Plastic and Reconstructive Surgery: Approaches and Techniques, Chichester: Wiley, 2015, p.660 [https://books.google.co.uk/books?id=tCq9BgAAQBAJ&pg=PA660#v=onepage&q&f=false Google books preview]</ref>
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